EVALUATION OF LIVER FIBROSIS IN LIVER BIOPSY OF ALCOHOLIC LIVER DISEASE CASES, WITH RETICULIN STAIN AND CD31 IMMUNOSTAIN

Background: Alcoholic liver disease (ALD) remains a major cause of morbidity and mortality world - wide. Liver biopsy is the gold standard method to assess presence fibrosis , useful in determining staging severity hepatic injury. To interpret biopsies, Reticulin stain, CD31,an immunohistochemical marker, which plays an important role degree disease, were used evaluation it. Methods: 50 Disease patients, evaluated for fibrosis, with H&E stain correlated CD 31 immunostaining expression by statistical analysis. Results: Strong positive correlation CD31 staining was seen among 34 cases (68%), moderate 8 (16%), mild 2 (4%), negative 6 (12%). Conclusion: The existence strong correlation, between revealed that methods are very much applicable assessing prognostic therapeutic strategies.